Advanced Nutriceuticals LLC dba The Guyer Institute of Molecular Medicine

CLOSEOUT LETTER Advanced Nutriceuticals LLC dba The Guyer Institute of Molecular Medicine MARCS-CMS 615908 — February 24, 2026 More Warning Letters Warning Letters About Warning and Close-Out Letters Delivery Method: Via Electronic Mail - Delivery and Read Receipt Requested Product: Drugs Recipient: Recipient Name Leonard D. Guyer, MD Recipient Title Owner and President Advanced Nutriceuticals LLC dba The Guyer Institute of Molecular Medicine 836 E. 86th Street Indianapolis , IN 46240-1806 United States Issuing Office: Division of Pharmaceutical Quality Operations Division III United States Secondary Issuing Offices United States Dear Dr. Guyer: The U.S. Food and Drug Administration (FDA) has completed an evaluation of your firm’s corrective actions in response to our warning letter, WL#615908, issued on November 10, 2021. Based on our evaluation, it appears that you have adequately addressed the violations contained in this warning letter. You are expected to take all necessary steps to ensure compliance with the Federal Food, Drug, and Cosmetic Act and FDA’s implementing regulations. This letter will not preclude any future regulatory action should violations be observed during a subsequent inspection or through other means. Sincerely, /S/ Matthew J. Lash Acting Director Office of Compounding Quality and Compliance Office of Compliance Center for Drug Evaluation and Research Content current as of: 03/17/2026 Regulated Product(s) Drugs